Fatal Flaws: How a Misfolded Protein Baffled Scientists and Changed the Way We Look at the Brain

Fatal Flaws: How a Misfolded Protein Baffled Scientists and Changed the Way We Look at the Brain

Jay Ingram


Discovered and pointed out because the reason behind mad cow sickness in basic terms 3 a long time in the past, the prion is a protein molecule that, whilst misshapen within the mind, turns into deadly. Novel and arguable, prions have provoked a systematic revolution. They problem the very foundations of biology: A disease-causing entity with out genetic fabric at all? A molecule able to infecting, multiplying, and killing? This booklet recounts the birth of prion technology and the inventive detective paintings scientists have undertaken as they struggle to discover the solutions to devastating mind illnesses from mad cow and Creutzfeldt-Jakob illness to Parkinson’s, Alzheimer’s, Lou Gehrig’s, and others.
 
As in each one of his best-selling books, Jay Ingram the following makes advanced clinical techniques available and exhibits how little-known occasions can have profound importance. He describes the improvement of prion technology as a rough-and-tumble affair, with opponents, eccentrics, interfering governments, and brilliantly inventive humans all taking part in salient roles. Weaving biology, drugs, human tragedy, discovery, and sour medical festival into his account, he unearths the lovely capability of prion technology, whose discoveries might free up the solutions to a few of humankind’s such a lot harmful diseases.

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